摘要
三拗汤及其后世历代衍化而成的类方系列,是中医治疗以咳嗽、哮喘为主证的呼吸病常用方剂,配伍宣肺祛风、宣泄化痰、宣肺化饮是其主要衍化形式。方中物质基础主要来源于其组方药材,但配伍后有效物质溶出量有变化,且有新成分产生。笔者通过多层次的效应评价发现,类方间既具有宣肺效应的共性特点,又存在据证衍化的优效性。其共性的效应途径涉及了保护结构细胞、抗炎、抗氧化和免疫调节等多个环节。
San＇ao Decoction（SD） and its analogous formulas derived in the following generations are common used prescriptions for treating pulmonary diseases with principal symptoms such as cough and asthma.They are usually compatible with Chinese herbs for facilitating Fei,dispelling wind,resolving phlegm and fluid retention.Material bases in these formulas are mainly derived from Chinese drugs,but dissolution contents of active componemts are changed and new components are produced after compatibility.By multilevel effect evaluation,these analogous formulas all have commonness in ventilating Fei and superiorities of evidence-based derivation.The effect pathway of commonness was involved in cell structure protection,anti-inflammation,antioxidant,and immuno-regulation.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2015年第11期1384-1387,共4页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金项目(No.81473580,No.1072748)
国家“十一五”技支撑计划项目(No.2006BAI06A02)
关键词
三拗汤
类方
宣肺
San＇ao Decoction
analogous formulas
facilitating Fei
