高强度聚焦超声治疗原发性肝癌相关并发症分析及处理

The associated complications analysis and treatment measures of high intensity focused ultrasound in the treatment of primary hepatic carcinoma

目的 对高强度聚焦超声（HIFU）治疗原发性肝癌的并发症进行分析,提高HIFU治疗的安全性.方法 回顾性分析郑州大学第一附属医院自2009年12月-2014年9月收治的165例经高强度聚焦超声治疗的原发性肝癌患者的资料,统计其发生的并发症并分析相关处理措施.结果 HIFU治疗原发性肝癌常见的并发症包括治疗区皮肤软组织损伤（118/165）、肝功能一过性损伤（83/165）、术后低热（81/165）、自限性胸腔积液（42/165）及术区疼痛麻木（33/165）;比较严重的并发症主要包括肋骨骨折（2例）、脏器穿孔损伤（1例）、癌灶破裂出血（1例）及皮肤Ⅱ（5例）、Ⅲ（1例）度烧伤;所有并发症积极治疗后均未引起严重后果.结论 高强度聚焦超声治疗原发性肝癌严重并发症少,安全性高.

Objective To investigate the complications of High Intensity Focused Ultrasound （HIFU） in the treatment of primary hepatic carcinoma,looked forward to improving the safety of the treatment of HIFU.Methods Retrospectively analyzed the clinical data of 165 patients with primary liver cancer treated by High Intensity Focused Ultrasound in the First Affiliated Hospital of Zhengzhou University from September 2014 to December 2009,to summarise the complications of this therapeutic method and analysis the related treatment measures.Results HIFU treatment of primary liver cancer common complications included the treatment of skin soft tissue injury （118/165）,a transient injury of liver function （83/165）,postoperative fever （81/165）,self-limiting pleural effusion （42/165） and postoperative pain （33/165）;The severe complications included rib fractures（2 cases）,organ perforation injury （1 case）,Cancer rupture hemorrhage （1 case）and Skin 1Ⅱ（5 cases）,Ⅲ（1 case） degree burn;Serious consequences were not caused by the complications which were actively treated.Conclusion The treatment of primary liver cancer by High Intensity Focused Ultrasound has less serious complications and high safety.