综合干预前后我院剖宫产围手术期抗菌药物使用调查

Survey of Perioperative Antimicrobials of Cesarean Section in Our Hospital before and after the Comprehensive Intervention

目的:调查综合干预前、中、后剖宫产围手术期抗菌药物使用情况,了解抗菌药物管理和干预效果,为促进合理用药提供依据。方法:分别抽取2011年10月—2012年3月(干预前)、2012年4月—2012年9月(干预中)、2012年10月—2013年3月(干预后)病历各80份,进行回顾性调查,对抗菌药物选择、联合用药、给药时机、疗程、费用、住院天数等进行统计分析。结果:干预后抗菌药物的品种选择主要是第一代或第二代头孢菌素,无联合用药,给药时机主要为钳夹脐带后,疗程大多控制在24 h内,抗菌药物使用费用明显降低。结论:通过我院各部门的综合干预,剖宫产围手术期应用抗菌药物已基本合理。

Objective： To investigate the use of perioperative antimicrobials in cesarean section before, during and after the comprehensive intervention, and to understand the effect of perioperative antimicrobial drug management and intervention measures, so as to provide a basis for further promoting the rational use of drugs.Methods：A total of 80 medical records before,during and after the comprehensive intervention,from the records of 2011.10-2012.03 （pre-intervention）, 2012.04-2012.09 （intervention）, 2012.10-2013.03 （after intervention） were respectively selected and surveyed retrospectively. The antimicrobials selection, combination therapy, timing of administration, period of treatment, cost, and days of hospitalization were comparatively analyzed.Results： After the intervention, the selection of antibiotics species is mainly ifrst or second-generation cephalosporins with no combination the rapy; timing of administration is mainly after cord clamping; the course has been basically controlled within 24h and antimicrobial drug costs were signiifcantly reduced.Conclusion： Perioperative use of antibiotics in cesarean section has become reasonable through hospital departments’ comprehensive intervention.