腹腔镜卵巢囊肿剥除术中不同止血方法对卵巢功能影响的研究

Study of different hemostasis of Laparoscopic ovarian cyst resection influence on ovarian function

目的:探讨腹腔镜卵巢囊肿剥除术中卵巢创面采用双极电凝或缝合止血方法对卵巢储备功能的影响。方法:选取卵巢良性囊肿行腹腔镜卵巢囊肿剥除术者80例,随机分成两组,每组40例,创面分别采用电凝或缝合方法止血,比较两组患者术前与术后6个月血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)和基础窦卵泡数(AFC),以及卵巢动脉收缩期峰值血流速度(PSV)的变化。结果:电凝组术后6个月FSH、LH水平较术前升高,E2水平降低,AFC、PSV也较术前明显下降,差异均有统计学意义(P<0.05);缝合组术后各项指标无明显变化(P>0.05)。结论:腹腔镜卵巢囊肿剥除术中,卵巢创面采用电凝止血对卵巢储备功能的影响大,采用缝合止血较电凝止血可以更好地保护卵巢功能。

Objective： To explore the influence of two kind hemostasis on ovarian reserve function in laparoscopic ovari- an cyst resection. The method of hemostasis included electro coagulation and suture. Method：80 patients experienced laparoscopic ovarian cyst resection were recruited, and were divided randomly into 40 cases in the electric coagulation hemostasis group and 40 cases in the suture hemostasis group. In order to evaluate the ovarian reserve function after operation, the change of serum follicle stimulating hormone（FSH）, luteinizing hormone（LH）, estradiol（E2 ） and the number of antral follicle（AFC）, ovarian artery peak systolic velocity（ PSV） were detected in the two groups preopera- tive and postoperative 6 months. Result：Compared to preoperative, the levels of FSH and LH increased after 6 months of operation in Electric coagulation hemostasis group, and level of E2 , AFC, PSV declined, and there were statistical difference （P〈0.05）. However, there was no any change compared preoperative with postoperative in the suture he- mostasis group. Conclusion： Electric coagulation hemostasis maybe influence on the ovarian reserve function heavily, but suture hemostasis has less influence on the ovarian reserve function.