晋中市居民尿碘及甲状腺疾病现况调查

Status of urinary iodine and thyroid diseases among residents in Jinzhong

目的：探讨晋中市居民尿碘及甲状腺疾病现况。方法选择晋中市第二人民医院2014年1月至2014年9月人群抽样调查中甲状腺疾病患者750例为观察组，抽取健康检查者500例为对照组，行空腹尿样标本采集，对比血清促甲状腺素、甲状腺过氧化物酶抗体（ TPOAb）、甲状腺球蛋白抗体（ TGAb）、游离三碘甲状腺原氨酸、游离甲状腺素、甲状腺B超及尿碘等，对比不同年龄组发生情况。结果晋中市居民尿碘处于适宜及过量水平。观察组平均尿碘浓度（312.8μg／L）居较高水平，与对照组（187.4μg／L）比较差异有统计学意义（ P＜0.05）。不同甲状腺疾病所检测的尿碘浓度均居较高水平，与对照组比较差异均有统计学意义（ P＜0.05）。结论补碘需结合个体差异，依据当地碘环境，合理、科学进行，以防碘过量，诱导甲状腺疾病，测定尿碘，可做为常规检测手段，以为临床提供依据。

Objective To investigate the status of urinary iodine and thyroid diseases among res-idents in Jinzhong.Methods From January 2014 to September 2014, Seven hundrad and fifty patients with thyroid disease in crowd sampling were selected as observation group, and five hundrad healthy per-sons were selected as control group.Fasting urine specimen collection, compared to serum TSH, thyroid peroxidase antibody （TPOAb）, thyroglobulin antibody （TGAb）, FT3, FT4, thyroid B ultrasound and u-rinary iodine of different ages were combared.Results The level of urimary iodine of residents in jinzhong was appropriate or excess.Urinary iodine concentration of observation group was 312.8 g/L, and that of control group was 187.4 μg/L, the difference was significant between the two groups （ P〈0.05 ） .Urinary iodine concentration in different thyroid disease was in the higher level than that of con-trol group, the difference was significant（ P〈0.05） .Conclusions Requires a combination of individu-al differences in iodine, iodine according to local environment, rational, scientific conduct, to prevent excess iodine induced thyroid disease, determination of urinary iodine, So it can be used as conventional testing methods, provide the clinical basis.