早期腹腔灌洗对重症急性胰腺炎治疗的临床意义

Clinical significance of early peritoneal lavage treatment for severe acute pancreatitis

目的：探讨早期腹腔灌洗对重症急性胰腺炎治疗的临床效果。方法选取鄢陵县人民医院2013年9月至2014年9月收治的66例重症急性胰腺炎患者作为研究对象，按照随机分组法将其分为对照组和观察组，对照组采取常规方法治疗，观察组在常规治疗基础上采取早期腹腔灌洗进行治疗，比较两组临床效果、住院时间以及腹水淀粉酶含量。结果观察组显效14例，有效16例，无效3例，总有效率为90.9％，对照组显效10例，有效12例，无效11例，总有效率为66.7％，观察组总有效率明显高于对照组，差异有统计学意义（ P＜0.05）；观察组住院时间和腹水淀粉酶含量明显优于对照组，差异有统计学意义（ P＜0.05）。结论早期腹腔灌洗不仅可明显提高重症急性胰腺炎的临床治疗效果，还能有效缩短住院时间，值得在临床推广应用。

Objective To investigate the effect of early peritoneal lavage in the treatment of pa-tients with severe acute pancreatitis.Methods From September 2013 to September 2014, 66 cases of severe acute pancreatitis were chosen as research subjects, and randomly divided into the control group and the observation group.The patients in control group were given conventional methods of treatment, and the patients in observation group were given early peritoneal lavage in addition.The clinical effects, hospital stay, and ascites amylase levels of the two groups were compared.Results After effective treat-ment, 14 cases were markedly effective, 16 cases were effective, 3 cases were invalid, the total effective rate was 90.9%in the observation group.Ten cases were markedly effective, 12 cases were effective, 11 cases were invalid, the total effective rate was 66.7%, there was significant difference in the total effective rate between the two groups（P〈0.05）.The hospitalization time and ascites amylase content in observation group was significantly better than that in the control group, the difference was significant （P〈0.05）. Conclusions Early peritoneal lavage not only can significantly improve the clinical effect of severe acute pancreatitis, but also effectively shorten the hospital stay, which is worth clinical application.