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环氧合酶2与神经系统疾病

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摘要 环氧合酶（cyclooxygenase,COX）又被称为前列腺素过氧化物合成酶,发现于19世纪90年代,是催化花生四烯酸（arachidonic acid,AA）合成各种前列腺素类（prostaglandins,PGS）及血栓素类的限速酶。研究表明,COX存在3种同工酶,即COX-1、COX-2、COX-3。COX-1在人体组织和细胞的表达相对恒定,参与人体正常功能的维持.
作者 张奎 吴世政 张淑坤
机构地区 青海大学研究生院 青海省人民医院神经内科
出处 《中华老年心脑血管病杂志》 CAS 2015年第11期1224-1226,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金 青海省自然科学基金资助(2013-Z-921)
关键词 前列腺素内过氧化物合酶类 花生四烯酸 神经系统疾病 海马 大脑皮质 杏仁核
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献29

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二级参考文献26

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共引文献25

中华老年心脑血管病杂志
2015年 第11期

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