期刊文献+

脂蛋白相关性磷脂酶A2与缺血性脑卒中的相关研究进展 被引量:10

下载PDF
导出
摘要 脑卒中为当今成年人致残的首要病因,是仅次于心血管疾病和肿瘤的第三大致死病因,87%脑卒中为缺血性脑卒中。脑卒中给家庭和社会带来巨大的经济和心理负担,预防和治疗脑卒中是一项重大的公共卫生问题。然而令人遗憾的是,对于脑卒中,尤其是缺血性脑卒中,至今尚无完善的治疗方法。临床迫切需要有确切意义的生化标记物,以早发现,早治疗,这也是解决脑卒中巨大危害的根本出路。
出处 《中华老年心脑血管病杂志》 CAS 2015年第11期1227-1229,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金 "十二五"国家科技支撑计划课题(2011BAI08B04) 山东省科技发展计划项目(2014GSF118106)
  • 相关文献

参考文献26

  • 1Krintus M,Kozinski M,Kubica J,et al.Critical appraisal of inflammatory markers in cardiovascular risk stratification.Crit Rev Clin Lab Sci,2014,51:263-279.
  • 2Rallidis LS,Tellis CC,Lekakis J,et al.Lipoprotein-associated phospholipase A(2)bound on high-density lipoprotein is associated with lower risk for cardiac death in stable coronary artery disease patients:a 3-year follow-up.J Am Coll Cardiol,2012,60:2053-2060.
  • 3Celik O,Ozturk D,Akin F,et al.Evaluation of lipoprotein-associated phosholipase A2and plaque burden/composition in young adults.Coron Artery Dis,2015,26:266-271.
  • 4Tselepis AF,Rizzo M,Goudevenos IA.Therapeutic modulation of lipoprotein-associated phospholipase A2(Lp-PLA2).Curr Pharm Des,2011,17:3656-3661.
  • 5Dullaart RP,van Pelt LJ,Kwakernaak AJ,et al.Plasma lipoprotein-associated phospholipase A2mass is elevated in STEMI compared to non-STEMI patients but does not discriminate between myocardial infarction and non-cardiac chest pain.Clin Chim Acta,2013,424:136-140.
  • 6Tellis CC,Moutzouri E,Elisaf M,et al.The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA2.J Lipid Res,2013,54:3394-3402.
  • 7Han X,Wang T,Zhang J,et al.Apolipoprotein CⅢregulates lipoprotein-associated phospholipase A2 expression via the MAPK and NFΚB pathways.Biol Open,2015,4:661-665.
  • 8Garg PK,McClelland RL,Jenny NS,et al.Lipoprotein-associated phospholipase A2and risk of incident cardiovascular disease in a multi-ethnic cohort:The multi ethnic study of atherosclerosis.Atherosclerosis,2015,241:176-182.
  • 9Ait-Oufella H,Mallat Z,Tedgui A.Lp-PLA2and sPLA2:cardiovascular biomarkers.Med Sci(Paris),2014,30:526-531.
  • 10Silva IT,Mello AP,Damasceno NR.Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A2(Lp-PLA2):a review.Lipids Health Dis,2011,10:170.

同被引文献106

引证文献10

二级引证文献47

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部