上消化道间质瘤侵袭危险性的相关因素分析

Upper gastrointestinal stromal tumor invasion-related risk factors analysis

目的:探究上消化道间质瘤侵袭危险性的相关因素。方法:选择2013年5月-2014年6月期间我院收治的已经病理学证实的80例上消化道间质瘤患者,对所有患者均行胃镜及超声内镜检查,分析上消化道间质瘤侵袭危险性的相关因素。结果:CIST患者根据危险性评估分为低度侵袭危险性组、高度侵袭危险性组两组。Logistic回归分析,低度侵袭危险性组患者与高度侵袭危险性组患者在超声内镜的肿瘤大小、肿瘤表面是否光滑、形态是否规则、回声是否均匀、边界是否清晰等特征存在显著性差异(P<0.05),在肿瘤生长方式、肿瘤患病部位等特征无差异性(P>0.05),说明这2项因素与肿瘤的侵袭危险无相关性。肿瘤大小是影响上消化道间质瘤侵袭危险性最危险的独立性因素因素(OR=4.745),表面是否光滑(OR=4.125)、形态是否规则(OR=4.065)、回声是否均匀(OR=3.854)、边界是否清晰(OR=3.687)也是影响上消化道间质瘤侵袭危险性的关键因素。结论:上消化道间质瘤侵袭危险性的相关因素有肿瘤大小、肿瘤表面是否光滑、形态是否规则、回声是否均匀、边界是否清晰等5个因素。内镜检查显示直径越大、表面不光滑甚至溃烂、回声不均匀、形态不规则、边界不清晰的上消化道肿瘤的侵袭危险性越大,反之,侵袭性越小。

Objective ：To explore the risk factors of gastrointestinal stromal tumor invasion. Methods： Gastrointes- tinal stromal tumors 80 patients pathologically confirmed, underwent endoscopy and endoscopic uhrasound. Results： Logistic regression analysis showed, EUS tumor size, tumor surface smooth, shape whether the rules, echo uniform, the boundary were a significant different （ P 〈 0.05 ） Logistic regression gradually analysis showed that the influence of tumor size was the most dangerous risk factor independent factors （OR = 4. 745 ）, the surface smooth （OR = 4. 125 ）, whether morphological rules （ OR = 4.065 ）, the echo uniform （ OR = 3. 854）, the boundaries clear （ OR = 3. 687 ） also the factors affecting gastrointestinal stromal tumor invasion. Conclusion：Upper gastrointestinal stromal tumor invasion - related risk factors are tumor size, tumor surface smooth, shape whether rules, echo uniform, the boundary clear.