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Notch信号通路与肿瘤发生发展研究进展

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摘要 Notch信号转导通路广泛存在，早期发现此通路的调节和激活通过与邻近细胞间的相互作用来调节调控机体各系统细胞和组织器官的分化。
作者 何宁 张静姝
机构地区 天津市疾病预防控制中心毒理室
出处 《毒理学杂志》 CAS CSCD 北大核心 2015年第5期380-382,共3页 Journal of Toxicology
关键词 NOTCH信号通路 肿瘤 癌转移
分类号 R457.7 [医药卫生—治疗学]
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参考文献18

  • 1魏秋芳,刘良裕,刘枫,涂志军,吕萌,周锟,余祖滔,潘斌,陈卓.Notch信号通路与肿瘤干细胞及抑制剂研究进展[J].中国药学杂志,2014,49(6):441-448. 被引量：4
  • 2Sriuranpong V,Vorges MW, Ravi RK, et al. Notch signaling induces cell cycle arrest in small cell lung cancer cells [ J]. Cancer Res,2001,61 (7):3200-3205.
  • 3Haruki N, Kawaguchi KS, Eichenberger S, et al. Dominant negative Notch3 receptor inhibits mitogen activated protein kinase pathway and the growth of human lung cancers [ J]. Cancer Res ,2005,65 (9) :3555-3561.
  • 4Zagouras P, Stifani S, Blaumueller CM, et al. Alterations in Notch signaling in neoplastic lesions of the human cervix [J]. Proc Natl Acad Sci U S A,1995(14):6414-6418.
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  • 6胡娜,宋毅,来卫东,刘琳琳,顾润国.Notch1、Jagged1在肝细胞癌组织中的表达及临床意义[J].中国医药导报,2013,10(19):4-7. 被引量：8
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  • 10Patel PN, Yu XM, Jaskula-Sztul R, et al. Hesperetin Activates the Notchl Signaling Cascade, Causes Apoptosis, and Induces Cellular Differentiation in Anaplastic Thyroid Cancer[ J] Ann Surg Oneol, 2014,21Suppl (4) : $497- 504.

二级参考文献93

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毒理学杂志
2015年 第5期

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