^(18)F-FDGPET-CT在脑转移瘤寻找原发灶的临床应用价值

Clinical Appllication of ^(18) F-FDG PET-CT in Detection of Primary Tumors of Brain Metastases

目的:探讨^(18)F-FDGPET-CT寻找脑转移瘤原发灶的临床应用价值。方法:回顾性分析120例行^(18)F-FDGPET-CT检查寻找原发病灶的脑转移瘤患者的病史资料,并与活组织病理结果及临床随访结果进行对照。结果:^(18)F-FDG PET-CT对脑转移瘤原发灶的检出率为79.2%,灵敏度为97.9%,特异性为86.9%,阳性预测值为96.9%,阴性预测值为90.9%,准确率为95.8%。结论:^(18)F-FDG PET-CT在寻找脑转移瘤原发灶中具有重要的临床应用价值,并为临床分期及治疗提供有利帮助。

Objective：To explore the clinical application of ^18F-FDG PET-CT in detection of primary tumors of brain metastases.Methods：The results of detection of primary tumors by ^18F-FDG PET-CT in 120 patients with brain metastases were retrospectively analyzed,and compared with pathological results or clinical follow-up.Results：The rate of^18F-FDG PET-CT to detect the primary tumors of brain metastases was79%,and the sensitivity,specificity,accuracy,positive predictive value and negative predictive value were97.9%,86.9%,95.8%,96.9%and 90.9%,respectively.Conclusion：^18F-FDG PET-CT contributes important value in finding brain metastases from unknown primary tumor,and is helpful for clinical staging and treatment.