大蒜生物活性成分降血压机制研究进展

Mechanisms Underlying the Antihypertensive Effects of Garlic Bioactives

主要从分子水平、生物化学和细胞理论角度分析总结大蒜的生物活性成分所有的抗氧化应激性,促进硫化物生成,抑制血管紧张素转换酶(ACE)活性、NF-κB的表达以及血管平滑肌细胞增殖等降血压机制的研究进展,为今后非药物降血压方法的研究以及临床医学和流行病学提供科学的理论参考。

This article summarized the advances on potential antihypertensive mechanisms of garlic bioactive components,such as the anti-oxidative stress,promoting sulfide formation,inhibiting angiotensin-converting enzyme（ACE） activity,the NF-κB expression and vascular smooth muscle cell proliferation.Which will Provide the scientific reference for future study on non-pharmacological methods of lowering blood pressure as well as clinical and epidemiological research.