多重因素对雨生红球藻虾青素积累的影响

Influences of Multiple Factors on Accumulation of Astaxanthin in Haematococcus pluvialis

虾青素独特的分子结构使其成为自然界最强的抗氧化剂,工业上成功利用雨生红球藻生产天然虾青素的生产模式均采取先藻细胞增殖、再虾青素积累的两步法,近年来用于积累虾青素的胁迫诱导方法仍然集中在高光照强度、高温、缺氮等传统典型胁迫条件,但开始倾向于这些方法的复合作用,同时也进行了异养培养、添加外源试剂、补充其他营养元素等多种尝试。

Astaxanthin is one of the most effective natural antioxidants due to its unique molecular structure and biological activity. At present, natural astaxanthin was produced by Haematococcus pluvialis as a two-step process involving microalgae proliferation and accumulation. The stress-induced method for accumulating astaxanthin was concentrated under high intensity lighting, elevated temperatures, nitrogen deficiency and other environmental stress conditions. These techniques were further refined and compounded to enhance its effectiveness over the last few years. Additional developments such as heterotrophic culture, the introduction of foreign sourced reagents and nutrients had also come into standardized practice.