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New players in ABA signaling: identification of PUB12/13 involved in degradation of ABA co-receptor ABI1 被引量:3

New players in ABA signaling: identification of PUB12/13 involved in degradation of ABA co-receptor ABI1
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摘要 Abscisic acid (ABA) was originally identified in the early 1960s, and was thought to be involved in fruit and leaf ab- scission. Over the past 50 years, ABA was intensely studied and has become one of the vital plant hormones implicated in seed dormancy, seed germination, stomatal regulation, flowering, senescence and environmental stress responses. Early work isolated the mutants abil (ABA-insensitive 1) and abi2, which are insensitive to ABA [1]. These two genes were subsequently revealed to encode members of the clade A protein phosphatase 2Cs (PP2Cs) of serine/threonine pro- tein phosphatases (see review [2]). Additional members of the clade A PP2Cs such as ABA-hypersensitive germinationl (AHG1) and AHG3, were also shown to participate in ABA stress signaling [2]. These PP2Cs function as negative regu- lators of ABA response. Abscisic acid(ABA)was originally identified in the early1960s,and was thought to be involved in fruit and leaf abscission.Over the past 50 years,ABA was intensely studied and has become one of the vital plant hormones implicated in seed dormancy,seed germination,stomatal regulation,flowering,senescence and environmental stress responses.
出处 《Science China(Life Sciences)》 SCIE CAS CSCD 2015年第11期1173-1174,共2页 中国科学(生命科学英文版)
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  • 1Koornneef M, Reuling G, Karssen CM. The isolation and characterization of Abscisic-Acid Insensitive mutants of Arabidopsis thaliana. Physiol Plantarum, 1984, 61:377-383.
  • 2Finkelstein R. Abscisic acid synthesis and response. In The Arabidopsis Book. 2013. 11:e0166.
  • 3Ma Y, Szostkiewicz I, Korte A, Moes D, Yang Y, Christmann A, Grill E. Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science, 2009. 324:1064-1068.
  • 4Park SY, Fung P, Nishimura N. Jensen DR. Fuiii H, Zhao Y, Lumba S. Santiago J, Rodrigues A, Chow TF. Alfi'ed SE, Bonetta D, Finkelstein R, Provart NJ, Desveaux D, Rodriguez PL. McConn P, Zhu JK, Schroeder Jl, Volkman BF, Cutler SR. Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Science. 2009. 324:1068-1071.
  • 5Melcher K, Ng LM, Zhou XE, Soon FF, Xu Y, Suino-Powell KM, Park SY, Weiner J J, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson FC, Jcnsen DR, Yong EL. Volkman BF, Cutler SR, Zhu JK, Xu HE. A gate-latch-lock mechanism for hormone signalling by abscisic acid receptors. Nature, 2009, 462:602-608.
  • 6Kong L, Cheng J, Zhu Y, Ding Y, Meng J, Chen Z, Xie Q, Guo Y, Li J, Yang S, Gong Z. Degradation of the ABA co-receptor ABllby PUBI2/13 U-box E3 ligases. Nat Commun, 2015, doi: 10.1038/ ncomms9630.

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