摘要
目的评价锥形束计算机断层扫描(CBCT)引导脑胶质瘤同步加量调强放疗(SIB-IMRT)技术的应用价值。方法选取我院2011年12月至2013年12月收治的脑胶质瘤患者60例,随机分为研究组及对照组,研究组行CBCT图像引导下SIB-IMRT技术,计划肿瘤区(PGTV)同步加量62.5 Gy/25次,33 d完成。对照组行三维适形放疗,60 Gy/30次,40 d完成。放疗过程中及放疗结束后评价两组毒性反应,放疗结束后、放疗后1年评价两组肿瘤局控率及生存率。结果研究组与对照组在放疗过程中及放疗结束后放疗毒性反应无统计学差异(P>0.05);两组有效率、疾病控制率、生存率有统计学差异(P<0.05)。结论 CBCT图像引导下SIB-IMRT技术缩短了治疗时间,提高肿瘤局控率及生存率,这对于脑胶质瘤患者有重要的科学意义和应用价值。
Objective To evaluate the curative effect of CBCT guide glioma SIB-IMRT radiotherapy technology. Methods In our hospital from December 2011 to December 2013, 60 patients with glioma were randomly divided into research group and the control group, research group performed the team line CBCT images guided glioma SIB-IMRT radiotlierapy technology, PGTV synchronization added quantity 62.5 Gy/25, completed in 33 days. The control group performed three-dimensional conformal radiation therapy, 60 Gy/30 times, completed in 40 days. During radiotherapy and after radiotherapy, evaluated the toxic effects, tumor local control rate and survival rate at the end of radiation therapy and after radiation therapy for 1 year of two groups. Results Radiotherapy toxicity reaction between two groups was no statistically significant difference during radiation therapy and after radiation therapy （P〉0.05） . The effectiveness, disease control rate and survival rate of two groups had significant difference （P〈0.05）. Conclusion CBCT images guided SIB-IMRT radiation technology can shorten the treatment time, increase the tumor local control rate and survival rate. For glioma patients, it has important scientific significance and application value.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第19期62-65,共4页
Chinese Journal of Clinicians(Electronic Edition)
