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小细胞肺癌患者外周血循环肿瘤细胞的表达及临床价值 被引量:3

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摘要 目的探讨小细胞肺癌患者外周血循环肿瘤细胞的表达及临床价值。方法选取小细胞肺癌患者67例为观察组,同期健康体检人员67例为对照组,均行外周血循环肿瘤细胞检测,比较2组外周血循环肿瘤细胞的阳性表达情况,分析外周血循环肿瘤细胞与临床特征、肿瘤标记物的关系。结果观察组外周血循环肿瘤细胞阳性表达率明显高于对照组,外周血循环肿瘤细胞计数明显多于对照组。患者体力状况(PS)评分越高,病理分期越高,发生远处转移例数及远处转移部位个数越多,神经元特异性烯醇化酶水平越高。乳酸盐脱氢酶越高时外周血循环肿瘤细胞阳性表达率越高。结论小细胞肺癌患者外周血循环肿瘤细胞的阳性表达率显著升高。外周血循环肿瘤细胞的升高幅度与PS评分、病理分期、远处转移、远处转移部位个数以及神经元特异性烯醇化酶和乳酸盐脱氢酶水平有关。
出处 《现代中西医结合杂志》 CAS 2015年第33期3733-3735,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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