患者基础疾病对持续性肾脏替代治疗管路寿命影响的多因素分析

Multiple Factors Analysis on Circuit Life Span Influenced by Underlying Diseases in Continuous Renal Replacement Therapy

目的:探讨基础疾病对连续性肾脏替代治疗(CRRT)中管路寿命的影响。方法:回顾性分析151例次接受连续性肾脏替代治疗的重症患者,记录患者高血压、冠心病、重症肺炎等基础疾病及管路寿命(小时),应用多因素线性回归及相关分析基础疾病对CRRT管路寿命的影响。结果:重症肺炎(b=-2.784,P=0.001)、高血压(b=-1.345,P=0.003)及手术患者(b=-1.184,P=0.034)管路寿命明显更短。结论:对持续性肾脏替代治疗管路寿命有影响的基础疾病因素是重症肺炎、高血压及手术。

Objective： To investigate the efficacy of underlying diseases on circuit life span in continuous venovenous hemofiltration（ CVVH） treatment. Methods： Retrospective analysis of 151 consecutive patients with CVVH,underlying diseases including hypertension coronary artery disease and severe pneumonia were recorded,multiple regression analysis and correlation analysis were used to analyze. Results： Severe pneumonia（ b =-2. 784,P = 0. 001） hypertension（ b =-1. 345,P = 0. 003） and surgery（ b =-1. 184,P = 0. 034） had shorter filter life span. Conclusion： Duration of circuit life span was significantly influenced by underlying diseases including severe pneumonia,hypertension and surgery.