摘要
目的:探讨聚桂醇局部注射治疗婴幼儿颌面部血管瘤的效果。方法:将100例颌面部血管瘤患儿随机分为鱼肝油酸钠加地塞米松组(A组,n=25)、平阳霉素加地塞米松组(B组,n=25)、聚桂醇组(C组,n=25)和聚桂醇加地塞米松组(D组,n=25),比较各组疗效及不良反应。结果:随访时间2-13个月,A组治愈10例、显效12例、有效1例,2例未能坚持治疗;B组治愈11例、显效10例、有效1例,3例未能坚持治疗;C组治愈18例、显效3例、有效3例,1例未能坚持治疗;D组治愈19例、显效3例、有效2例,1例未能坚持治疗。C、D组的治愈率明显高于A、B组(P<0.05),且C、D组硬化注射后腹部不适和低热的不良反应明显少于A、B组(P<0.05)。结论 :以聚桂醇为主的硬化剂局部注射治疗婴幼儿颌面部血管瘤的疗效好,副作用少。
Objective:To explore the effects of lauromacrogol injected locally for infant oral and maxillofacial hemangioma. Methods:100 infants with oral and maxillofacial hemangioma were randomly divided into sodium morrhuate combined with dexamethasone group (group A,n=25), pingyangmycin combined with dexamethasone group (group B,n=25), lauromacrogol group (group C,n=25), and lauromacrogol combined with dexamethasone (group D, n=25). The clinical effects and adverse reactions were compared among the four groups. Results:In group A,10 cases were cured,12 cases markedly effective,1 case effective and 2 cases lost. In group B,11 cases were cured,10 cases markedly effective, 1 case effective and 3 cases lost. In group C,18 cases were cured,3 cases markedly effective,3 case effective and 1 case lost. In group D,19 cases were cured ,3 cases markedly effective, 2 case effective and 1 case lost. The cured rate was significantly higher in group C and group D than that in group A and group B (P 〈0.05),while the adverse reactions such as abdominal discomfort and low fever were significantly lower in group C and group D than those in group A and group B(P 〈 0.05). Conclusion: It is effect and less adverse reactions for infant oral and maxillofacial hemangioma treated by lauromacrogol injected locally.
出处
《岭南急诊医学杂志》
2015年第5期398-399,417,共3页
Lingnan Journal of Emergency Medicine
关键词
聚桂醇
颌面部血管瘤
婴幼儿
局部注射
疗效
lauromacrogol
oral and maxillofacial hemangioma
infant
effect
local inject