原发性肝脏神经内分泌癌的CT特征

CT features of primary hepatic neuroendocrine carcinoma

目的探讨原发性肝脏神经内分泌癌(PHNEC)的CT特征。方法回顾性分析7例经手术病理证实的PHNEC的CT检查资料,均行平扫及增强检查。结果 7例患者均无肝硬化,单发3例,2例位于肝右叶,1例位于肝左叶;4例多发,表现为单个较大肿块伴多发子灶。CT平扫均为实性低密度肿块或结节,边界清晰。动态增强扫描5例动脉期不均匀明显强化,其中3例门脉期持续强化呈不均匀稍高密度,2例门脉期开始廓清呈低密度。2例单发病灶动脉期轻度强化,门静脉期持续强化,延迟期呈相对低密度。结论 PHNEC的CT表现具有一定的特征性,CT检查有助于术前诊断。

Objective To investigate the CT features of primary hepatic neuroendocrine carcinoma（PHNEC）. Methods Unenhanced and dynamic contrast-enhanced CT of 7 patients with pathologically confirmed PHNEC was analyzed retrospectively.Results Of 7 patients without liver cirrhosis, the tumors were solitary（3） in the right lobe（2） and left lobe（1）, or single large lesion with multiple satellite nodules（4）. On CT, 5 lesions were low-density masses or nodules with well-defined boundary and heterogeneous marked contrast enhancement in the arterial phase progressively enhancing（3） or washing out in the portal venous phase（2）. The remaining 2 solitary lesions enhanced slightly in the arterial phase continuing into the portal venous phase and washing out in the parenchymal phase. Conclusion CT features can aid pre-operative diagnosis of PHNEC.