经皮穴位电刺激联合地西泮口服治疗创伤后酒精戒断综合征心理渴求的临床观察

Clinical observation of transcutaneous acupoint electrical stimulation combined diazepam oral in the treatment of posttraumatic psychological craving for alcohol withdrawal syndrome

目的研究经皮穴位电刺激联合地西泮口服治疗创伤后酒精戒断综合征患者在躯体戒断期心理渴求的临床疗效。方法选择2011年1月—2014年1月收治的由于突发性创伤导致的四肢某部位骨折或关节、软组织损伤等需禁止或减少饮酒的患者120例作为研究对象,随机分为对照组和观察组各60例。对照组患者给予地西泮口服治疗,10 mg/次,2次/d;观察组在对照组的基础上给予经皮穴位电刺激治疗,30 min/次,2次/d;并由心理咨询师给予个性化的心理健康教育指导。于干预后第1、2周应用酒精戒断综合自评量表(alcohol withdrawal integrated self rating scale,AWSS)及焦虑自评量表(selg-rating anxiety scale,SAS)评价两组患者的临床治疗效果。计量资料组间比较采用t检验,组内比较采用配对t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果观察组干预后第1、2周AWSS及SAS评分分别为(9.53±0.34)、(3.57±0.35)、(49.11±2.69)、(30.87±0.87)分,显著低于对照组的(14.09±0.17)、(7.21±0.30)、(68.34±2.17)、(49.88±0.56)分,差异均有统计学意义(均P<0.05)。观察组对于饮酒"十分想"心理渴求率为3.33%,低于对照组的35.00%,差异有统计学意义(P<0.05)。结论经皮穴位电刺激联合地西泮口服治疗创伤后酒精戒断综合征患者,可显著减轻患者躯体戒断期的心理渴求,有效改善患者停止饮酒后发生的严重戒断反应,值得临床推广应用。

Objective To study the clinical effect of transcutaneous acupoint electrical stimulation combined diazepam oral in the treatment of posttraumatic psychological craving for alcohol withdrawal syndrome. Methods 120 cases of limb fracture or joint soft tissue injury who need to prohibition of alcohol were selected and randomly divided into control group and observation group（n=60）. The patients in control group were treated with diazepam oral, 10 mg/time, 2 times/d; patients in observation group were treated with transcutaneous acupoint electrical stimulation on the basis of control group, 30 min/time,2 times/d; and by the psychological consultant to guide individualized psychological health education. The clinical effect after treatment 1,2 weeks were evaluated by alcohol withdrawal integrated self rating scale（AWSS） and selg- rating anxiety scale（SAS）. Measurement data between groups were processed by t test, in groups were processed by paired- t test, count data was processed by chi square test, P〈0.05 was considered statistically significant. Results The AWSS and SAS of observation group after treatment for 1, 2 weeks were（ 9.53±0.34） 、（ 3.57±0.35） 、（ 49.11±2.69） 、（ 30.87±0.87） points, lower than that of control group [（ 14.09 ±0.17） 、（ 7.21 ±0.30） 、（ 68.34±2.17） 、（ 49.88±0.56） points], the differences were statistically significant（all P〈0.05）. The rate of psychological craving for drinking was 3.33% in observation group, lower than that in control group（35.00%）, the difference was statistically significant（P〈0.05）. Conclusion Transcutaneous acupoint electrical stimulation combined diazepam oral in the treatment of posttraumatic psychological craving for alcohol withdrawal syndrome can effectively reduce the psychological craving for drinking, improve the serious withdrawal reaction occurs after stop drinking, worthy of clinical application.