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葛花提取物对小鼠急性酒精肝损伤治疗及预防作用的研究 被引量:5

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摘要 目的:研究葛花乙醇提取物对小鼠急性酒精肝的保护及预防作用。方法:采用酒精灌胃制备急性酒精性肝损伤小鼠模型,小鼠在隔夜禁食后,以15ml/ml的剂量灌胃56度红星二锅头,每日灌胃一次,连续7d。末次染毒后处死小鼠,制备肝匀浆,检测血清谷丙转氨酶(ALT)、谷草转氨酶(AST)的含量。结果:在姜黄素对小鼠急性酒精性肝损伤的研究中发现,ALT的变化是较为明显的,AST的变化不是很明显。由此可以说明,姜黄素对小鼠肝脏的保护是有局限性的。如果搭配其他药物,效果应该会进一步提升。
出处 《生物技术世界》 2015年第9期165-165,167,共2页 Biotech World
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