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红细胞omega-3指数气相色谱-质谱检测方法的建立与应用 被引量：2

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摘要 Omega-3（又称ω-3或n-3）多不饱和脂肪酸（PUFA）主要包括亚麻酸、二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）。大量研究表明，ω-3PUFA可能具有保护心血管、
作者 程雅婷 李维 赵蓓蓓 朱庆义
机构地区 广州金域医学检验中心
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2015年第11期768-770,共3页 Chinese Journal of Laboratory Medicine
基金 广州市医药卫生科技项目（20141A011102）
关键词 omega-3 质谱检测 气相色谱 红细胞 多不饱和脂肪酸 Omega-3 二十二碳六烯酸 应用
分类号 R446.11 [医药卫生—诊断学]
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参考文献14

  • 1Dietary supplementation with vitamin E after myocardial n-3 polyunsaturated fatty acids and infarction: results of the GISSI- Prevenzione trial. Grappo Italiano per to studio della Sopraw'ivenza ne]J' Infarto MioeartJico ~ J ~. Lancet, 1999, 354 (9177) : 447-455.
  • 2Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsatura-ted fatty acids after myocardial infarction : time-course analysis of the results of the GruppoItalianoper 10 studio della Sopravvivenza nell' Infarto Miocardio (GISSI) - Prevenzione[ J]. Circulation, 2002, 105 (16) : 1897-1903.
  • 3Markhus MW, Skotheim S, Graft IE, et al. Low Omega-3 Index in Pregnancy Is a Possible Biolo-gical Risk Factor for Postpartmn Depression[J]. PLoSONE, 2013, 8(7): e67617.
  • 4Wang JH, Eguchi K, Matsumoto S, et al. The oJ-3 Polyunsaturated Fatty Acid, Eicosapentaenoic Acid, Attenuates Abdominal Aortic Aneurysm Developmentvia Suppression of Tissue Remodeling[J]. PLoS ONE, 2014, 9(5) : e96286.
  • 5Brenna JT, Carlson SE. Docosahexaenoic acid and human brain development: Evidence that a dietary supply is needed for optimal development[J]. J Hum Evol, 2014, 77(2) :99-106.
  • 6Koren N, Simsa-Maziel S, Shahar R, et al. Exposure to omega-3 fatty acids at early age accelera-te bone growth and improve bone quality[J]. J Nutr Biochem, 2014, 25(6) : 623-633.
  • 7Haugen MA, Kjeldsen-Kragh J, Bjervea KS, et al. Changes in plasma phospholipid fatty acids and their relationship to disease activity in rheumatoid arthritis patients treated with a vegetarian diet[J]. BrJNutr, 1994, 72(4): 555-566.
  • 8Harris WS, yon Schacky C. The Omega-3 Index: a new risk factor for death from coronary heart disease [ J]. Prev Med, 2004, 39 (1): 212-220.
  • 9Harris WS. Omega-3 Fatty Acids and Cardiovascular Disease: A Case for Omega-3 Index as a New Risk Factor [ J ]. Pharmacol Res, 2007, 55(3) : 217-223.
  • 10Dodds ED, McCoy MR, Rea LD, et al. Gas chromatographic quantification of fatty acid methyl esters : flame ionization detection vs. electron impact mass spectrometry [ J ]. Lipids, 2005, 40 (4) : 419-428.

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中华检验医学杂志
2015年 第11期

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