针刺治疗小儿脑瘫疗效的Meta分析

Meta Analysis of the Efficacy of Acupuncture Treatment for Infantile Cerebral Palsy

目的系统评价针刺治疗小儿脑瘫的疗效。方法通过全面搜索维普、万方、CNKI等数据库中已发表的关于针刺治疗小儿脑瘫临床随机对照试验的相关文献,并手工查阅关于小儿脑瘫相关图书资料,运用系统评价方法,按照排除纳入标准筛选文献,整理资料,评价文献质量,提取文献。并采用Rev Man5.2软件进行质量评价和Meta分析。结果共纳入3个随机对照试验,共含343例患者。结果显示有效的合并效应量OR及95%CI[OR:3.14,95%CI(1.34,7.36),Z=2.63]。各研究组间无统计学异质性(P=0.88,I2=0%),治疗组和对照组两组差异有显著统计学意义(P=0.009)。结论说明针刺对小儿脑瘫有较好的疗效,但还需要更多高质量、规范化的临床随机对照试验进一步验证支持。

Objective To evaluate the effect of acupuncture treatment for infantile cerebral palsy. Methods Through comprehensive searching VIP, Ten thousand party, CNKI database published clinical randomized controlled trials of acupuncture treatment of infantile cerebral palsy of related literature, and the manual referring to relevant books and materials on infantile cerebral palsy, using system evaluation method, according to rule out into the standard selection literature, data were sorted, literature quality was evaluated, and extraction of literatures were extracted. And we used the Rev Man5.2 software to make quality evaluation and Meta analysis. Results Three randomized controlled trials were involved, including 343 patients. The results showed that the effective consolidation effect quantity OR and 95% CI（ OR： 3.14, 95% CI（ 1.34, 1.34）, Z = 2.63）. No significant heterogeneity between the three groups（ P = 0.88, I2 =0%）. Differences between the two groups had significant statistical significance（ P = 0.009）. Conclusion Acupuncture for infantile cerebral palsy had better curative effect. But still need more high quality, standardization of clinical randomized controlled trials further validation-support.