亚健康主因素诱发大学生肥胖的生物学机制

The Biological Mechanisms of College Students' Obesity Causing by Sub-health

亚健康是世界范围内发生率较高的"亚临床"症状,对人们的生活质量影响较大。特别是大学生群体,受学习、就业压力及不良行为习惯等方面的干扰,致使亚健康的发生率和肥胖程度逐年攀升。因此,分析亚健康引发肥胖的生物学机制是发现其内在机理问题的关键点。经综述证实,躯体亚健康(躯体不适和睡眠问题)和心理亚健康(抑郁、焦虑)是亚健康发生率增高的主要征象。躯体亚健康是受交感神经亢奋、Ghrelin释放水平增加,胰岛素分泌增多、神经系统紊乱、皮质醇激素中断、交感神经和迷走神经平衡功能异常,中枢神经系统的应激能力下降等影响。而心理亚健康是受神经系统功能失调等影响。这两种生物学途径是引发大学生肥胖的终极因素。

Sub--health is a higher incidence of subclinical symptoms of the worldwide, which has a great impact on people＇s life quality. Especially for the college students, with the interference of learning pressure, employment pres sure and bad habits, the incidence of sub--health and levels of obesity is higher and higher year by year. Therefore, the analysis of biological mechanisms of sub--health resulting in the obesity is the key to find its inner mechanism. Proved by the review, somatic sub--health （physical discomfort and sleep quality） and psychological sub--health （de- pression, anxiety） are the main sign of increasing incidence of sub--health. The factors which impact on physical sub --health includes： sympathetic excitement, increasing of Ghrelin release and insulin secretion, the disorders of nerv- ous system, the interruption of hormone cortisol, the balance dysfunction of sympathetic and vagus nerve, the de- creased of the stress ability of central nervous system and others. But psychological sub--health is influenced by the dysfunction of nervous system. These two biological ways are the ultimate factors to trigger obesity of collegestudents.