肠粘连缓解汤加减辨治粘连性肠梗阻的临床研究

Clinical study on the decoction treatment of adhesive intestinal obstruction with intestinal adhesions

目的：探讨肠粘连缓解汤加减辨治粘连性肠梗阻患者的临床疗效。方法：选择2011年3月~2013年5月在我院诊治的120例粘连性肠梗阻患者,随机分为实验组和对照组,每组患者60例。对照组患者给予石蜡油治疗,实验组患者服用肠粘连缓解汤治疗,观察两组患者治疗后一般临床症状、炎症因子的变化以及比较两组患者的临床治疗效果。结果：治疗后,实验组患者的肛门排气时间、症状消失时间以及气液平消失时间均小于对照组,胃液排出量显著小于对照组,各项指标较对照组均具有统计学意义（P〈0.05）;实验组患者的WBC计数、CRP、IL-6、IL-8炎症因子的水平均较对照组患者低,具有显著性差异（P〈0.05）;实验组患者的总有效率为95.0%,较对照组患者高（71.7%）,具有明显差异性（P〈0.05）。结论：肠粘连缓解汤加减辨治粘连性肠梗阻患者,能够显著降低肛门排气时间、症状消失时间以及气液平消失时间,减少胃液排出量,降低炎性因子水平,提高临床治疗效果。

Objective： To investigate the clinical efficacy of adhesions ease decoction treatment for adhesive intestinal obstruction in patients with intestinal barrier. Methods： A total of 120 cases of intestinal obstruction patients admitted in our hospital between March 2011 and May 2013 were recruited for the study. The subjects were then randomly divided into experimental group and control group, with 60 cases in each group of patients. Patients in control group received paraffin treatment, and the patients in experimental group were administrated with adhesions ease soup treatment. Changes in general clinical symptoms were observed after treatment, changes in inflammatory factors and clinical outcomes were compared between two groups. Results： After treatment, patients in the experimental group exhibited significant less flatus, time, and liquid level symptoms than the control group. Moreover, the gastric excretion in the experimental group was significantly lower than the control group （P 〈 0. 05）. WBC count, CRP, IL - 6, IL - 8 levels of inflammatory cytokines in the experimental group patients were significantly lower than in the control group （ P 〈 0. 05 ）. In addition, the patients of experimental group showed a total effective rate of 95.0% compared with the control group of patients （71.7%）, a significant difference was observed （ P 〈0. 05 ）. Conclusion： The treatment of adhesions ease decoction can significantly reduce flatus, time, and liquid level symptoms disappear time, reduce gastric excretion and reduce the level of inflammatory factors, improved clinical outcomes in patients with intestinal barrier with adhesive intestinal obstruction .