纸质包装材料中芳香胺向食品模拟物改性聚苯醚的迁移量测定

Determination of Migration of Aromatic Amines from Paper Packaging Materials into Food Simulant Tenax

为了解纸质包装材料中芳香胺向食品中的迁移量,选取改性聚苯醚（Tenax）作为食品模拟物,建立了溶剂萃取/气相色谱-质谱联用法测定纸质包装材料和Tenax中芳香胺的方法。对样品前处理和气相色谱-质谱检测条件进行优化。纸质包装材料样品选取10 m L叔丁基甲醚为溶剂超声萃取30 min,Tenax选取10 m L正己烷为溶剂超声萃取15 min。萃取液经DB-17弹性毛细管柱分离,选择离子监测模式测定,内标法定量,3个内标分别为萘-d8、2,4,5-三氯苯胺和蒽-d10。结果表明,在0.001 4~0.14 mg/dm2范围内,20种芳香胺的线性关系良好,相关系数（r）均大于0.998,相对标准偏差（RSD）为1.9%~6.9%,检出限为0.000 1~0.000 3 mg/dm2,加标回收率为80.6%~107.2%。该方法应用于两种纸质包装材料中芳香胺迁移量的测定,显示分子量偏小、沸点偏低的芳香胺有一定迁移。该方法简单快速,灵敏度高,重现性好,能满足纸质包装材料中20种芳香胺迁移量的测定要求。

In order to investigate the migration of aromatic amines from different paper packaging materials into foods,a solvent extraction / gas chromatography- mass spectrometric（ GC- MS） method was developed for the detection of aromatic amines in paper packaging materials and food simulants,using modified polyphenylene oxide（ Tenax） as food simulant. The pretreatment method of sample and GC- MS condition were studied. The paper packaging material sample was extracted by ultrasonic extraction for 30 min using 10 m L tert-butyl methyl ether as solvent. The Tenax sample was extracted by ultrasonic extraction for 15 min using 10 m L n-hexane as solvent. The extract was separated with a DB- 17 capillary column under selected ion monitoring（ SIM） mode. The targets were quantitatively analyzed by the internal standard method using naphthalene-d8,2,4,5-trichloroaniline and anthracene-d10 as three internal standards for the corresponding aromatic amines. The calibration curves of 20 aromatic amines were linear in the range of 0. 001 4- 0. 14 mg / dm2,with correlation coefficients（ r） greater than 0. 998 and detection limits of 0. 000 1- 0. 000 3 mg / dm2. The relative standard deviations（ RSD） ranged from 1. 9% to 6. 9%, and the recoveries were in the range of80. 6%- 107. 2% for both paper packaging material sample and Tenax. The method was applied in analysis of the migration of aromatic amines in two types of paper packaging materials. The results in-dicated that the small molecular weight and low boiling point aromatic amines had a certain degree of migration under the investigated conditions. The method was simple,quick,sensitive and reproducible,and could meet the requirement for the determination of the migration of aromatic amines in paper packaging materials.