药物筛选新技术及其应用进展

Drug Screening New Technologies and Their Applications

药物筛选是应用适当的筛选方法和筛选技术从海量化合物中筛选出具有药理活性的化合物的方法,是提高研发效率、缩短周期、减少成本、降低风险、使新药研发能够持续进行的关键。药物筛选新技术的开发已成为医药科学研究的重要内容。该文就近年来发展的药物筛选新技术及其应用进行了简要综述。

Drug screening is to apply the appropriate screening methods and screening technologies to extract the pharmacological active compounds from vast amounts of compounds. Drug screening is the key to improve the drug research efficiency,accelerate research cycle,cut down research cost and reduce investment risk,which makes the new drug research and development can be sustained. Drug screening new technologies have also become the important content of pharmaceutical research. More and more drug screening technologies have been developed,such as high throughput screening technology,high content screening technology,surface plasmon resonance technology and microfluidic chip technology,etc. These new drug screening technologies and their application are reviewed in this article.