检测血清降钙素原和内毒素在肺部感染患者的诊断价值

Diagnostic value of procalcitonin and endotoxin examination in patients with pulmonary infection

目的探讨检测血清降钙素原(PCT)和内毒素在肺部感染患者诊断中的价值。方法按病原学诊断标准,临床肺部感染评分(CPIS)≥6分的患者98例分为细菌组(B组,67例)和非细菌组(NB组,31例),检测两组血清PCT和内毒素水平,分析其在肺部感染患者病原学诊断中的价值。结果 B组血清PCT和内毒素均高于NB组(P<0.05)。血清PCT水平对CPIS≥6分的B组患者诊断敏感度为95.5%,特异度为100%,均高于内毒素的83.6%和87.1%(P<0.05)。结论监测血清PCT对CPIS≥6分的肺部感染患者具有较好的诊断价值。

Objective To investigate the diagnostic value of procalcitonin（PCT）and endotoxin examinations in the patients with pulmonary infection.Methods According to the diagnostic criteria of pathogens,ninety-eight patients with clinical pulmonary infection score（CPIS）≥6points were assigned into two groups of B（bacterial pulmonary infection,67 cases）and NB（non-bacterial pulmonary infection,31 cases）.Serum levels of PCT and endotoxin were determined and the significance of PCT and endotoxin examinations in the diagnosis of the patients with CPIS≥6points was evaluated.Results Serum levels of PCT and endotoxin were significantly higher in group B than those in group NB（P〈0.05）.The sensitivity and specificity of PCT in group B were 95.5% and100%,respectively,which were significantly higher than 83.6% and 87.1% of endotoxin（P〈0.05）.Conclusion Detection of serum level of PCT has a better significance in the pathogen diagnosis of the pulmonary infectious patients with CPIS≥6points.