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老年高血压患者非对称二甲基精氨酸与动脉硬化及左心室舒张功能的相关性

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摘要 目的探讨老年高血压患者非对称二甲基精氨酸(ADMA)与动脉硬化及左心室舒张功能的关系。方法采用ELISA法检测85例老年高血压患者血清ADMA水平,全自动动脉硬化测量仪测定臂踝脉搏波传导速度(baPWV),彩色多普勒超声检查仪测量左心室舒张功能相关指标。结果老年高血压患者ADMA与baPWV水平、舒张早期血流速度峰值(E)/二尖瓣环舒张早期运动速度峰值(E′)呈正相关(r=0.715、0.251,P<0.01或P<0.05),与E′呈负相关(r=-0.234,P<0.05)。baPWV与E/E′呈正相关(r=0.390,P<0.01),与E′呈负相关(r=-0.383,P<0.01)。结论血清ADMA可能成为预测和评估老年高血压患者动脉硬化及左心室舒张功能的重要指标。
出处 《江苏医药》 CAS 2015年第21期2576-2577,共2页 Jiangsu Medical Journal
基金 江苏省自然科学基金(BK2011382)
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