多种儿科疾病外周血T淋巴细胞亚群的检测

RELATIONSHIP BETWEEN T LYMPHOCYTE SUBTYPE AND MULTIPLE DISEASES IN CHILDREN

①目的 探讨T淋巴细胞亚群异常与相关疾病的关系。②方法 采用单克隆抗体间接免疫荧光法对 1171例受检者进行外周血T细胞亚群检测 ,并与正常健康人进行对照。③结果 除缺铁性贫血 (IDA)外 ,再生障碍性贫血 (AA)、原发性血小板减少性紫癜 (ITP)、自身免疫性溶血性贫血 (AIHA)、多数呼吸系统疾病、结缔组织疾病以及单纯性肾病综合征都存在T淋巴细胞亚群异常。④结论 小儿常见疾病大多存在T淋巴细胞亚群异常。

Objective\ To explore the relationship between disorder of T lymphocyte subtype and some related diseases. Methods\ T lymphocyte subtype of peripheral blood in 1 171 patients was examined with indirect immunofluorescence of monoclonal antibody and compared with healthy persons.\ Results\ The disorder of T lymphocyte subtype was found in aplastic anemia (AA), primary thrombocytopenic purpura (ITP), antoimmune hemolytic anemia (AIHA), most respiratory diseases, connective tissue diseases and nephrotic syndrome, but not in iron deficiency anemia(IDA).\ Conclusion\ The abnormal T lymphocyte subtype exist in most common diseases in children.