天麻菊花咀嚼片的研制

Preparation of Gastrodia elata-Chrysanthemum chewable tablet

以天麻粉作为主药,辅以菊花粉,选择适宜的填充剂和黏合剂制备天麻菊花咀嚼片,并优化其配方。首先,测定咀嚼片不同位置的L*、a*、b*值,计算标准差和极差,分析不同填充剂对咀嚼片颜色均匀程度的影响。通过质构测定并结合感官评价,分析不同黏合剂对咀嚼片质构特性的影响。最后,采用响应面分析法研究天麻菊花咀嚼片的最优配方。实验结果表明:采用微晶纤维素作为咀嚼片的填充剂,标准差和极差最小,咀嚼片颜色最均匀;采用明胶作为黏合剂,质构特性最佳;最优配方为微晶纤维素32%、明胶17%,天麻粉目数为200目。

Using gastrodia elata powder as main raw materials, mixed with chrysanthemum, and chose suitable filling agent and adhesive, gastrodia elata-chrysanthemum chewable tablet was made and the recipe was optimized. Firstly, the L＊, a＊, b＊ of different position in chewable tablet was measured, the standard deviation and range were calculated to analyze the effect of different filling agent on the appearance color uniformity of the tablet. Second, the influence of different adhesives on the texture characteristics was evaluated by the texture profile analysis and sensory evaluation. Lastly, response surface methodology was employed to analyze the optimal formula of the chewable tablets. The results indicated that microcrystalline cellulose had the minimum standard deviation and range among all the filling agents, with its color most evenly. And Gelatin had the best structure characteristics as adhesive. The best formulation of the chewable tablet was microcrystalline cellulose 32% and gelatin 17%, with 200 mesh gastrodia elata powder.