动物性短肽螯合物研究进展

Advances progress in animal peptide chelates

短肽螯合物是通过短肽N-端氨基、C-端羧基、氨基酸侧链以及肽链中的羰基和亚氨基与金属离子配位形成,具有易吸收、营养价值好、生物效价高等优点,以及抗菌、抗氧化、降血糖降血脂、免疫调节等诸多生物活性。综述了动物性短肽螯合物的制备、结构分析、生物活性以及构效关系等方面的国内外研究现状,并展望其发展前景。

The peptide chelates complex, which is produced from chelating reaction between the N-terminal amino group and C-terminal carboxyl of short peptide, the side chains of amino acid, the carbonyl and imino of the peptide chain and metal ions. It have many advantages include easy absorbability, good nutrition, high biological potency and many special biological activities, example, antibacterial, antioxidant, hypoglycemic, lowering blood pressure, and immune regulation. The thesis is about the prepared process and the structural analysis of the chelation, which had been studied in recent years at home and abroad. Besides, some other biological activity and structure-activity relationship of the chelate polypeptide-metal complex were also covered. The potential development of the animal peptide chelates complex were analysed in the last.