疏肝健脾化痰法联合帕罗西汀片治疗肝郁痰扰型广泛性焦虑症临床疗效观察

Clinical observation on treating general anxiety disorder by the Shugan Jianpi Huatan therapy plus Paroxetine tablets

目的:探讨对肝郁痰扰型广泛性焦虑症患者采用疏肝健脾化痰法联合帕罗西汀片进行治疗所取得的临床疗效。方法:选择2012年10月-2014年10月来本院就诊的肝郁痰扰型广泛性焦虑症患者72例,随机分为观察组36例及对照组36例,其中观察组患者以疏肝健脾化痰法联合帕罗西汀片进行治疗,对照组患者单纯以帕罗西汀片进行治疗,观察两组患者汉密尔顿焦虑量表评分变化情况、临床疗效及不良反应。结果:在治疗之后,观察组中患者汉密尔顿焦虑量表评分变化情况明显优于对照组(P<0.05);观察组中患者临床总有效率为94.4%,对照组中患者总有效率为88.9%,观察组临床疗效明显优于对照组(P<0.05);观察组中患者的不良反应发生率为11.1%,对照组中患者的不良反应发生率为27.8%,两组存在显著差异(P<0.05)。结论:采用疏肝健脾化痰法联合帕罗西汀片治疗广泛性焦虑症的临床效果较显著,能够使患者的焦虑症状得到明显改善,取得较高的临床有效率,并且不良反应少,可在临床上进行推广应用。

Objective： To study clinical efficacy of the Shugan Jianpi Huatan therapy plus Paroxetine tablets on general anxiety disorder. Methods： 72 cases were randomly divided to the observation group （36 cases） and the control group （36 cases）. The observation group was treated by the Shugan Jianpi Huatan therapy plus Paroxetine tablets; the control group was treated only with the Paroxetine tablets. Hamilton Anxiety Scale score, clinical efficacy and adverse reactions of tables in two groups were compared. Results： After treatment, Hamilton Anxiety Scale score in the observation group was significantly lower （P〈0.05）; the clinical total efficiency in the observation group （94.4%） were significantly better than 88.9% in the control group （P〈0.05）. The adverse reaction rate in the observation group （11.1%） were significantly lower （P〈0.05）. Conclusion： Treating generalized anxiety disorder by the Shugan Jianpi Huatan therapy plus Paroxetine tablets can achieve a higher clinical efficiency, is worthy of promotion.