止渴养阴胶囊治疗2型糖尿病临床疗效分析

Clinical curative analysis of treatment of type 2 diabetes mellitus by Zhike Yangyin capsule

目的:观察止渴养阴胶囊治疗2型糖尿病的疗效。为中医药治疗2型糖尿病奠定基础,为预防和治疗糖尿病的大血管并发症提供方向和依据。方法:采用自身前后对照方法。观察84例2型糖尿病患者服用止渴养阴胶囊治疗前后对主要中医临床症状及糖化血红蛋白(Hb A1C)、空腹血糖浓度(FPG)、餐后2 h血糖浓度(2 h PG)的影响,治疗疗程为3个月。结果:根据中医证候疗效的比较,该实验有效率高达90.0%,治疗前后有统计学意义(P<0.05),两组治疗前后比较,FPG、2 h PG、Hb A1C(P<0.05),Hb Alc、FPG、2 h PG有显著性差异(P<0.05)。结论:在中医辨证论治的理论指导下,用止渴养阴胶囊通过益气养阴补脾益肾法来治疗气阴两虚型T2DM患者,可有效改善T2DM患者的临床症状和体征,降低血糖、糖化血红蛋白,且安全、有效,具有广泛的应用前景,值得进一步深入研究。

Objective： To observe the curative effect of zhikeyangyin capsule in the treatment of type 2 diabetes mellitus in order to lay the foundation for the treatment of type 2 diabetes mellitus, and provide direction and basis for the prevention and treatment of large vascular complications of diabetes. Method： By the method of self- control 84 cases of patients with type 2 diabetes were treated by providing thirst Yangyin capsule for 3 months and TCM clinical efficacy and symptoms, glycosylated hemoglobin（Hb A1c） along with fasting plasma glucose（FPG）, postprandial 2 hours blood glucose（2 h PG） impact were observed and compared after the treatment. Results： The comparison of TCM efficacy before and after treatment in the two groups showed that the treatment experiment has efficiency as high as 90.0%,and do possess statistical significance（P〈0.05）.FPG、2 h PG. Hb A1c（P〈0.05）, Hb Alc, FPG, 2h PG. have significant difference（P〈0.05）. Conclusion： Under the guidance of theory in the Traditional Chinese Medicine on the treatment of, with thirst, nourishing Yin capsule by supplementing qi and nourishing Yin fill spleen and tonifying kidney to treat patients with syndrome of deficiency of both qi and Yin T2 DM, can effectively improve T2 DM patients with clinical symptoms and signs, lowering blood glucose, glycosylated hemoglobin, and is safe and effective, with a wide range of applications, it is worth further study.