Biphasic通气模式在早产儿中的应用

Effect of Biphasic Positive Airway Pressure in Preterm Infants

目的:探讨使用经鼻双相正压通气(bi Phasic)在早产儿救治中的应用。方法:比较分析60例早产合并呼吸窘迫综合征以及原发性呼吸暂停患儿,分别应用鼻塞持续气道正压(nasal continuous positive airway pressure,NCPAP)和Bi Phasic模式治疗,从上机时间、需改有创机械通气例数等进行比较。结果:Bi Phasic治疗组患儿的上机时间和改有创机械通气例数均较NCPAP组明显减少,而且在保障有效通气的前提下呼吸末压力较NCPAP组为低,两组比较差异均有统计学意义(P<0.05)。结论:经鼻双相正压通气可作为早产儿合并RDS及呼吸暂停的首选治疗措施之一,明显优于NCPAP,尽早正确使用可以使许多患儿避免有创通气。

Objective： To investigate the using of nasal biphasie positive airway pressuro（BiPhasie） in preterm infants.Method： 60 proterm infants with respiratory distress syndrome and primary apnea were compared and analysized, who were applied nasal continuous positive airway pressure（NCPAP） and BiPhasie mode treatment respectively, the time from the machine and needed to change the number of cases of invasive mechanical ventilation were compared.Result： The BiPhasic group computer time and the number of the changing of invasive mechanical ventilation was significantly reduced which compared with NCPAP group, and the promise of ensuring effective ventilation of the end of the breath pressure was lower than the NCPAP group, the difference was statistically significant（P〈0.05）.Conclusion： Nasal biphasie positive airway pressure can be used as one of the treatment of respiratory distress syndrome and primaryapnea, significantly better than NCPAP, as soon as the proper using can make many preterm infants avoiding invasive ventilation.