2种不同麻醉方式对老年前列腺汽化电切除术患者术后早期认知功能的影响

Effect of two Different Anesthesia Methods on Senile Prostate Electrovaporization of Early Postoperative Cognitive Function of Patients

目的：观察2种不同麻醉方式对老年前列腺汽化电切除术患者术后早期认知功能的影响。方法：将80例ASAI-Ⅱ级经尿道前列腺电切术患者随机分为全身麻醉组（A）和硬膜外麻醉组（B），每组各40例。采用简易智力状态检查（MMSE）评分评估患者术前24小时、术后12小时、24小时、48小时、72小时的认知功能。结果：A组患者MMSE值在术后12小时、24小时明显降低，差异有统计学意义（P〈0．05），术后48小时、72小时恢复至术前24小时水平．差异无统计学意义（P〉0．05）。B组MMSE值在术后各时点与术前比较差异均无统计学意义（P〉0．05）。与B组相比，A组MMSE值在术后12小时、24小时点显著降低（P〈0．05）。结论：全身麻醉比硬膜外麻醉更容易引起老年前列腺汽化电切除术患者术后24小时内POCD的发生。

Objective： To observe the effect of two different anesthesia methods on senile prostate electrovaporization of early postoper- ative cognitive function of patients. Methods： 80 cases of ASAI -Ⅱ transurethral resection of the prostate were randomly divided into general anesthesia group （A） and epidural anesthesia group （B）, d0 patients in each group. Using mini mental state examination （MMSE） score in evaluation of patients with preoperative 24h, 12h, 24h, 48h, 72h, cognitive function. Results： A group of patients with MMSE after 12h, 24h decreased significantly, the difference was statistically significant （P 〈0. 005 ）, after 48h, 72h returned to the preoperative level of 24h, no significant difference （ P 〉 0.05 ）. The value of MMSE in B group at each time point after operation were compared before and after treatment were not statistically significant （ P 〉 0.05 ）. Compared with B group, A group, MMSE value in the 12h after the operation, 24 point decreased significantly （ P 〈 0. 005 ）. Conclusion ： General anesthesia is more likely to cause the occur-rence of Senile Prostate transurethral resection after 24h POCD than epidural.