小儿过敏性紫癜与肺炎支原体、幽门螺旋杆菌感染的相关性

The Association Mycoplasma Pneumonia and Heficobacter Pylori for Children with Allergic Purpura

目的：探讨小儿过敏性紫癜与肺炎支原体、幽门螺旋杆菌感染的相关性。方法：选择2011年7月～2014年12月，在福州儿童医院就诊的新发过敏性紫癜的患儿112例为病例组，同期非过敏性紫癜患儿112例为对照组。采用应用凝集法进行一MP检测，采用13C标记的尿素法检测幽门螺杆菌。分析小儿过敏性紫癜与肺炎支原体、幽门螺旋杆菌感染有无相关性。结果：病例MP阳性者34例，阳性率为30．35％。对照组12例，阳性率为10．71％；病例组C13呼气试验阳性者30例，阳性率为26．79％，对照组16例，阳性率为14．29％。病例组MP和C13阳性率显著高于对照组（P〈0．05）；肺炎支原体感染后幽门螺杆菌感染的优时比OR=2．83。结论：小儿过敏性紫癜与肺炎支原体、幽门螺旋杆菌感染有相关性。

Objective： The purpose of this study was to evaluate the association between mycoplasma pneumonia and helicobacter pylori infection in patients with allergic purpura. Methods： From July 2011 to Dec 2014 we selected 112 children diagnosed of allergic purpura in our hospital as the cases group and other non allergic purpura children as the control group. Using the MP antibody array and C13 array to evaluated the mycoplasma and helieobacter pylori infection. Results： 34 children were tested for MP positive in case group and 78negative; In control group the MP positive was 12 and negative was 100. The MP and C13 positive rate in case group were statistical higher than that of control group（P 〈0.05） ; The odds ratio for helicobacter pylori infection was OR =2.83. Conclusion： Strong and sig- nificant correlation between mycoplasma pneumonia and helicobacter pylori was found for children with allergic purpura