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新的非甾体抗炎药物氯诺昔康 被引量:40

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摘要 氯诺昔康是新的非甾体抗炎药。临床试验显示氯诺昔康可替代盐酸吗啡、盐酸哌替啶和盐酸曲吗多等止痛药 ,减轻外科病人术后疼痛。氯诺昔康可有效地减轻骨关节炎、类风湿性关节炎、强直性脊椎炎等疾病的疼痛。象其它的非甾体抗炎药一样 ,氯诺昔康最主要的不良反应是胃肠道症状。与其它昔康类药物相比 ,其特点是半衰期较短 (3~ 5h) ,临床用药剂量较小 (4~ 8mg) ,因此不良反应较轻。它具有很好的镇痛、抗炎作用 ,有口服和非肠道剂型 ,是很有市场前景的镇痛。
出处 《解放军药学学报》 CAS 2002年第4期215-217,共3页 Pharmaceutical Journal of Chinese People's Liberation Army
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