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ICU监护联合重组组织型纤溶酶原激活剂静脉溶栓治疗急性脑梗死30例疗效观察 被引量:10

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摘要 目的探讨神经ICU应用重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗急性脑梗死的效果。方法ICU内用rt-PA静脉溶栓治疗发病4.5h内急性脑梗死30例,观察治疗后神经功能缺损量表(NIHSS)评分变化、疗效和不良反应发生情况。结果治疗后3h,6h,12h,24h,7d,14dNIHSS评分较治疗前降低,差异有统计学意义(P<0.05),在治疗后出现非症状性颅内出血1例(3.3%),颅外出血(包括上消化道、呼吸道和皮肤黏膜等)2例(6.7%)。结论在ICU严密监测下,对急性脑梗死发病4.5h内给予rt-PA静脉溶栓治疗疗效显著,不良反应出现率低,安全可行。
出处 《贵州医药》 CAS 2015年第7期595-597,共3页 Guizhou Medical Journal
基金 贵州省国际科技合作计划项目[黔科合外G字(2014)7019号] 贵州省社会攻关计划[黔科合LH字(2014)7018号] 贵州省科学技术基金计划[黔科合J字(2011)2281号]
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参考文献9

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