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复方缬沙坦氢氯噻嗪片对中老年原发性高血压的疗效及血管内皮调节功能的影响 被引量:9

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摘要 已有大量研究表明,高血压患者存在血管内皮功能障碍,其所导致的内皮素(ET)和一氧化氮(NO)代谢失衡可能参与了原发性高血压的病理生理过程。内皮素有3种同分异构体家族,分别为ET-1、ET-2、ET-3,他们差别在于氨基酸的残基不同,对心血管起主要作用的是ET-1。
出处 《实用临床医药杂志》 CAS 2015年第21期132-133,共2页 Journal of Clinical Medicine in Practice
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