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替吉奥单药治疗高龄食管癌15例疗效分析 被引量:6

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摘要 目的探讨替吉奥单药治疗高龄食管癌疗效。方法回顾性分析15例行替吉奥单药化疗的高龄食管癌患者的临床资料。结果完全缓解(CR)0例,部分缓解(PR)9例,稳定(SD)5例,进展(PD)1例,总有效率60.0%(9/15),临床获益率93.3%(14/15);13例(86.7%)患者进食梗阻有不同程度的改善。结论对于无法手术的高龄食管癌患者,可采用单药替吉奥化疗的治疗方法,可缓解食管癌病情并提高生活质量且延长生命。
机构地区 仙居县人民医院
出处 《现代实用医学》 2015年第10期1359-1360,共2页 Modern Practical Medicine
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  • 1Torre L A,Bray F,Siegel R L,et al. Global cancer statistics, 2012 [J]. CA~A Cancer Journal for Clinicians,2015,65(2) : 87-108.
  • 2Chen W,Zheng R,Baade PD,et al. Cancer statistics in China, 2015 [J]. CA:A Cancer Journal for Clinicians,2016,66(2) : 115-132.
  • 3van Meerten E,Eskens FA,van Gameren EC,et al. First- line treatment with oxaliplatin and capecitabine in pa- tients with advanced or metastatic oesophageal caneer:a phase II study [J]. Br J Cancer,2007,96(9) :1348-1352.
  • 4Koizumi W, Boku N,Yamaguchi K, et al. Phase II study of S-1 plus leuc0vorin in patiefits with metastatic eolorectal cancer [J]. Annals of Oncology, 2010,21 (4) :766-771.
  • 5Kawa'hara M. Efficacy of S-1 in. non-small cell tung can- cer [J]. Expert Opin Pharmaeother, 2014,15 (13):1927- 1942.
  • 6Akutsu Y,Kono T,Uesato M,et al. S-1 monotherapy as sec- ond-or third-line chemotherapy for. unresectable and~recur- rent esophageal squamous cell earcinoma [J]. Oncology, 2013,84(5) : 305-310.
  • 7Ajani JA,Ilson DH,Daugherty K,et al. Activity of taxol in patients with squamous cell carcinoma and adenocarci- noma of the esophagus [J]. J Natl Cancer Inst, 1994,86 (14):1086-1091.
  • 8Nukatsuka M,Fujioka A, Nakagawa F,et al. Antimetastatic and anticancer activity of S-I, a new oral dihydropyrim- idine -dehydrogenase -inhibiting fluoropyrimidine,alone and in combination with paclitaxel in an orthotopically implanted human breast cancer model [J]. Int J Oncol, 2004,25(6):1531-1536.
  • 9Nakamura T,Ota M,Narumiya K,et al. [Docetaxel plus S-1 as a second-line chemotherapy for metastasis or re- currence of esophageal cancer] [J]. Gan To Kagaku Ry- oho, 2012,39 (2) : 227 -230.
  • 10Sandler AB, Kindler HL, Einhorn LH, et al. Phase II trial of gemcitabine in patients with previously untreated metastatic cancer of the esophagus or gastroesophageal junction [J]. Ann Oncol, 2000,11 (9) : 1161-1164.

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