微型钛血管吻合夹吻合血管的生物力学研究

Biodynamic study of vascular anastomosis with microclips

目的从生物力学角度评价应用微型钛血管吻合夹吻合小血管的安全可靠性。方法对80只新西兰大白兔的双侧颈动脉一侧应用微型钛血管吻合夹行端-端吻合,另一侧行间断端-端缝合吻合作对照,测定术后第1h、7、14及30d离体血管吻合口的平均最大抗张强度和平均最大破裂压。结果术后7d内吻合夹法的吻合口最大抗张强度高于针线吻合法(P<0.05),14d后无统计学差异(P>0.05);术后30d内两种吻合法吻合口的最大破裂压无统计学差异(P>0.05)。结论从生物力学角度表明应用微型血管吻合夹吻合小血管是安全可靠的。

Objective To evaluate the safety and reliablity of the vascular anastomosis with titanium microclips in terms of biodynamics. Methods A comparative experimental study was performed in 80 rabbits. One side of carotid arteries was anastomosed with titanium anastomotic microclips, the other side was anastomosed with sutures.The vessels were harvested at the 1st hour, 7th day, 14th week, and 30th day after operation. The average maximal stretch breaking force(AMSBF)and the average maximal breaking pressure (AMBP)of the anastomosis was measured by biodynamic method. Results AMSBF with microclips was stronger than that with sutures within 7 days postoperative(P< 0.05);but differences of AMSBF between the two methods were not significant after the 14th day postoperative(P >0.05). There were no significant differences of AMBP between the two methods(P >0.05).Conclusion The anastomosis technique with microclips is safe and reliable in terms of biodynamics.