高刺激率ABR与儿童良性阵发性眩晕的相关性

Correlation between high stimulus rate auditory brainstem responses and benign paroxysmal vertigo in children

目的探讨高刺激率听性脑干诱发电位(ABR)在诊断儿童良性阵发性眩晕(Benign ParoxysmalVertigo of children,BPV)的临床价值。方法根据BPV诊断标准,选取BPV的儿童60例和非BPV对照组20例。BPV组根据眩晕病程进展分为2周内眩晕发作组和无眩晕发作组。所有入组病例行听力学检查,对纯音测听听阈阈值、声导抗、高刺激率ABR进行比较,分析BPV及对照组之间听力学特征差异。结果(1)BPV组60例患儿及对照组20例儿童纯音测听、声导抗检查结果全部正常,听力无显著性差异。(2)BPV组中高刺激率ABR异常率为41.7%(25/60),正常对照组高刺激率ABR异常率为0%(0/20),两者有统计学差异,P<0.01。BPV组中:2周内眩晕发作组和无眩晕发作组,分别进行高刺激率ABR检查:2周内眩晕发作组高刺激率ABR异常率为63.6%(21/33),而2周内无眩晕发作者高刺激率ABR异常率为14.8%(4/27),两者有统计学差异,P<0.01。结论高刺激率ABR与儿童BPV、尤其是发作期的BPV具有一定的相关性。

Objective To study correlation between high stimulus rate auditory brainstem responses and benign paroxysmal vertigo（BPV） in children. Methods Included in the study were 60 children with BPV and20 normal children. The children with BPV were divided into two subgroups depending on whether there were attacks in past two weeks. Pure tone audiometry, acoustic immitance and high stimulus rate auditory brainstem response test were conducted in all groups, and the differences were analyzed. Results 1） Pure tone audiometry and acoustic immitance were normal in both BPV and normal control group. 2） The rate of abnormal high stimulus rate ABRs was 41.7 %（25/60） in BPV groups and 0% in the control group（p〈0.01）. 3）The rate of abnormal high stimulus rate ABRs was 63.6 %（21/33） in those with vertigo attacks in past 2weeks and 14.8 %（4/27） in those without vertigo attacks in past 2 weeks（p〈0.01）. Conclusions High stimulus rate ABR results appear to be correlated with BPV attacks in Children.