脑脊液置换术治疗蛛网膜下腔出血的临床研究

Clinical research of cereral spinal fluid displacement in the treatment of subaraclmoid hemorrhage

目的 探讨脑脊液置换术治疗蛛网膜下腔出血（SAH）的临床效果。方法 选取2013年2月~2015年4月我院收治的40例急性SAH住院患者作为研究对象,按照随机数字表法将其分为观察组和对照组,每组20例。对照组采取常规治疗,观察组在常规治疗基础上行脑脊液置换术,观察两组患者术后并发症发生情况、神经功能缺损评分以及临床疗效。结果 观察组术后并发迟发性脑血管痉挛、脑积水的发生率显著低于对照组,差异有统计学意义（P〈0.05）。治疗前,两组患者神经功能缺损评分差异无统计学意义（P〉0.05）;治疗后,两组患者神经功能缺损评分均低于治疗前（P〈0.05）,且观察组的神经功能缺损评分低于对照组,差异有统计学意义（P〈0.05）。观察组的治疗总有效率为90.00%,显著高于对照组的65.00%,差异有统计学意义（P〈0.05）。结论 脑脊液置换术能改善SAH患者的神经功能缺损评分,提高临床疗效,减少并发症的发生。

Objective To explore the clinical effects of cereral spinal fluid displacement in the treatment of subara- clmoid hemorrhage （SAH）. Methods 40 eases of acute SAH admitted into our hospital from February 2013 to April 2015 were selected as research object.They were divided into observation group（20 cases） and control group（20 cases） according to rardom number table method.The control group was treated with conventional treatment,the observation group was treated with cereral spinal fluid displacement on the basis of conrentional treatment.The complication,neural functional deficit score and clinical effect in two groups were compared. Results The incidence rate of delayed cerebral vasospasm and waterhead in observation group were lower than those of control group,the difference was significant （P〈 0.05）.Before treatment,the neural functional deficit score had no statistical significance between two groups （P〉0.05）.Af- ter treatment,the neural functional deficit score in two groups was lower than before treatment （P〈0.05）,and the neural functional deficit score in observation group was lower than that of control group（P〈0.05）.The total effective rate in ob- servation group was 90.00%,which was significantly higher than 65.00% of control group （P〈0.05）. Conclusion The cereral spinal fluid displacement can improve the neural functional deficit score of patient with SAH,increase the clini- cal effects and reduce the complication.