环磷腺苷葡胺注射液治疗缺血性心肌病合并心力衰竭的临床效果

Clinical effect of meglumine adenosine cyclophosphate injection in the treatment of ischemic cardiomyopathy combined with heart failure

目的 探讨环磷腺苷葡胺注射液治疗缺血性心肌病合并心力衰竭的临床效果。方法 选取本院2011年2月~2013年6月收治的80例缺血性心肌病合并心力衰竭患者作为研究对象,随机分成观察组与对照组,各40例。对照组采用常规方式治疗,观察组在对照组的基础上给予环磷腺苷葡胺注射液治疗,比较两组的治疗效果。结果观察组的总有效率为95.0%,显著高于对照组的70.0%,差异有统计学意义（P〈0.05）。两组治疗4周后的HR、LVEF、SVI、CI水平显著优于治疗前,差异有统计学意义（P〈0.05）。观察组治疗4周后的HR、LVEF、SVI、CI水平显著优于对照组治疗4周后,差异有统计学意义（P〈0.05）。结论 环磷腺苷葡胺注射液治疗缺血性心肌病合并心力衰竭的临床效果显著,能够改善心功能分级。

Objective To explore the clinical effect of meglumine adenosine cyclophosphate （MAC） injection in the treat- ment of ischemic cardiomyopathy （ICM） combined with heart failure. Methods 80 patients with ICM combined with heart failure from February 2011 to June 2013 in our hospital were selected and randomly divided into the treatment group and the control group,40 cases in each group.The control group was treated with routine therapy,the treatment group was given MAC injection on the basis of the control group.The clinical efficacy in two groups was compared. Results The total efficacy rate in the treatment group was 95.0%,which was higher than 70.0% in the control group,with signifi- cant difference （P〈0.05）.The level of HR,LVEF,SVI and CI after treatment for 4 weeks in two groups was better than that before treatment,with significant difference （P〈0.05）.The evel of HR,LVEF,SVI and CI after treatment for 4 weeks in the treatment group was better than that in the control group,with significant difference （P〈0.05）. Conclusion The clinical effect of MAC injection in the treatment of ICM combined with heart failure is significant,which can improve heart function degree.