摘要
目的通过分析单抗类抗肿瘤药使用情况,了解其使用现状、短期疗效及不良反应,为临床合理用药提供参考。方法收集2013年上半年中山市某三甲医院使用单抗类抗肿瘤药物的病例310例,摘录患者基本资料、用药情况及治疗期间出现的不良反应,对其使用情况进行分析,并结合住院时长分析短期疗效。结果单抗类抗肿瘤药物收费数量、金额占抗肿瘤药物收费总数量、总金额的0.12%和13.67%左右。241例(78%)单次疗程住院时长在14天以内,没有出现严重不良反应。298例(96%)顺利完成化疗疗程。结论单抗类抗肿瘤药物临床疗效良好,不良反应多为轻中度化疗反应,经处理后能恢复,但由于价格昂贵,限制了临床的应用。
Objective To know the current situation of the Monoclonal antibodies target anticancer drugs by collecting and analyzing data,to provide reference for the clinical reasonable application. Methods We collected310 cases used the antibodies target anticancer drugs in the hospital of Zhong Shan,analyzed its clinical efficacy,and evaluated the drugs＇ efficacy combining the time be hospitalized. Results The sum and number of charges of the Monoclonal antibodies targeted anticancer drugs are 13. 67 percent and 0. 12 percent in the total charges of anticancer drugs. There are 241 cases（ 78%） hospitalized in a single course of treatment within 14 days; 298（ 96%） completed the chemotherapy successfully. Conclusion The monoclonal antibodies targeting anticancer drugs has the good clinical efficacy,and most of the adverse reactions are mild or moderate which can recover after treated. The key factor limited the clinical application of the monoclonal antibodies targeted anticancer drugs is the price.
出处
《现代医院》
2015年第4期93-96,共4页
Modern Hospitals
关键词
单抗类
靶向抗肿瘤药物
病历分析
Monoclonal Antibodies
Targeted Anticancer Drugs
Medical Records Analysis
