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乳腺叶状肿瘤病理形态学特点与免疫表型分析

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摘要 目的分析乳腺叶状肿瘤的形态学特点,探讨其免疫表型的病理临床意义。方法收集90例乳腺叶状肿瘤患者临床病理资料,对其临床及病理形态学特点与免疫表型进行回顾性分析。结果肿瘤间质过度增生;恶性叶状肿瘤VEGF、p53、K-i67的阳性表达率分别为66.6%(6/9)、88.8%(8/9)、77.7%(7/9),良性叶状肿瘤VEGF、p53、K-i67的阳性表达率分别为1.58%(1/63)、3.2%(2/63)、0(0/63),结论良性、交界性、恶性乳腺叶状肿瘤形态学存在交叉性,良恶性差别大;VEGF、p53及K-i 67可做为判断肿瘤生物特性的重要参考指标。
出处 《泰山医学院学报》 CAS 2015年第4期422-424,共3页 Journal of Taishan Medical College
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