脑微出血相关因素分析

Related factors analysis of cerebral microbleeds

目的分析脑微出血(cerebral microbleeds,CMBs)的相关危险因素。方法收集576例头颅磁共振受检者,对CMBs进行分区、计数、分级。分析CMBs与临床因素的相关性。结果 576例受检者共检出353个CMBs灶,皮层-皮层下区92个,基底节-丘脑区184个,幕下区77个。Pearson相关性分析显示CMBs发生与年龄、高血压病、收缩压、舒张压、脑白质脱髓鞘、腔隙性脑梗塞有相关性,P<0.05。Logistic回归分析显示年龄、高血压病、脑白质脱髓鞘病变、腔隙性脑梗塞与CMBs发生有相关性,P<0.05。结论 CMBs出现在基底节丘脑区比例最高。年龄、高血压病、脑白质脱髓鞘、腔隙性脑梗塞与CMBs的发生有相关性,并且是CMBs发生的危险因素。

Objective：To analyze the risK factors of cerebral microbleeds（ CMBs）. Methods：A total of 576 patients with cerebrovascular diseases underwent examinations of magnetic resonance imaging（ MRI）of the brain,and the brain re-gions,number and grades of the CMBs were analyzed for the correlation between CMBs and clinical factors. Results：576 subjects were detected 353 CMBs lesions. There were 92 lesions in cortex and subcortical areas,184 lesions in basal gan-glia and thalamus areas and 77 lesions under the curtain area. Pearson correlation analysis showed that the occurrence of CMBs was associated with the patients’ age,hypertension,systolic blood pressure,diastolic blood pressure,cerebral white matter demyelination and lacunar infarction（P〈0. 05）. Logistic regression analysis showed that the occurrence of CMBs was associated with the patients’age,hypertension,cerebral white matter demyelination and lacunar infarction（P〈0. 05）. Conclusion：CMBs occurs most frequently in the basal ganglia and thalamus areas. The occurrence of CMBs is associated with the patients’ age,hypertension,cerebral white matter demyelination and lacunar infarction,which are the risK factors of CMBs occurrence.