规范管理妊娠期糖尿病对妊娠结局的影响

Analysis of normative management of gestational diabetes mellitus on pregnancy outcome

目的探讨妊娠期糖尿病对孕产妇并发症及围生儿并发症的影响。方法回顾性分析在我院分娩的120例妊娠期糖尿病患者,按其不同的治疗情况分成两组:观察A组为取得规范治疗后,血糖控制能达标的70例,观察B组为孕36周后确诊GDM,但未配合治疗、血糖控制不能达标者,共50例;选择同期未发生糖尿病的正常孕产妇60例作为对照组,对孕产妇情况以及围生儿发生的并发症进行比较。结果观察B组孕妇发生高血压、感染、羊水过多、产后出血、胎膜早破、酮症酸中毒以及剖宫产的机率均比对照组要高;同时,围生期发生的死胎、巨大儿、早产、窒息、新生儿低血糖或者高胆红素血症情况也都比对照组要高,差异均有统计学意义(P<0.05)。观察A组与对照组比较差异均无统计学意义。结论妊娠期糖尿病会极大影响孕产妇及围生儿的健康,一定要加强孕期监测和管理,减少母婴并发症。

Objective ： To investigate the effect of gestational diabetes mellitus on the maternal complications and perina- tal complications. Methods： A retrospective analysis of normal pregnant women in our hospital was made with 120 cases of gestational diabetes as the observation group and non diabetes 60 cases as the control group. The comparative analysis of maternal and perinatal complications was made. Results： In the observation group B, pregnant hypertension, infection, polyhydramnios, postpartum hemorrhage, premature rupture of membranes, ketosis acid medium, cesarean section were higher than those in the control group ;at the same time, in the observation group B, perinatal fetal death, fetal maeroso- mia, premature, asphyxia neonatal hypoglycemia, hyperbilirubinemia of newborn were significantly higher than those in the control group, the difference of two groups had statistical significance. In the comparison between group A with the control group, the differences was not statistically signifieant. Conclusion： Gestational diabetes mellitus has obvious effect on the maternal complications and perinatal pregnancy, which calls for the need to strengthen management and reduce the compli- cations of mothers and infants.