痰热清治疗急性黄疸型甲型肝炎患儿疗效观察

Effects of Tanreqing on children with acute jaundice hepatitis A

目的 观察痰热清注射液联合天晴甘美针剂治疗甲型肝炎儿童患者临床疗效。方法 系统回顾2010年8月至2013年4月在我科确诊并住院治疗甲型肝炎患儿116例,以2010年8月至2011年12月收治患儿60例为对照组,给予肌苷针剂、维生素C针剂联合天晴甘美针剂治疗2~3周。治疗组为2012年1月至2013年4月收治甲型肝炎患儿56例,给予天晴甘美针剂联合痰热清针剂治疗。结果治疗组患儿临床症状改善率和肝功能复常率明显优于对照组,有效率89.28%,差异有显著意义（P=0.002）。结论痰热清注射液治疗甲型肝炎患儿疗效显著,优于常规用药治疗。

Objective To observe the treatment effect of Tanreqing combined with magnesium isoglycyrrhizinate on hospitalized children with acute jaundice hepatitis A. Methods The clinical data of 116 hospitalized children with acute jaundice hepatitis A in our hospital from August 2010 to April 2013 were analyzed retrospectively. The control group （60 cases from August 2010 to December 2011） were treated with magnesium isoglycyrrhizinate injection combined with inosine injection and vitamin C injection for 2 weeks. The treatment group （56 cases from January 2012 to April 2013） were given Tanreqing injection combined with Magnesium isoglyeyrrhizinate for 2 weeks. Changes of the main symptoms, signs, key indicators of liver function （ALT, ALB and TBil） in patients were observed before and after treatment, and the clinical effects were analyzed. Results Clinical symptoms improvement rate, liver function recovery rate and the duration of treatment group were superior to the control group, and the effective rate of treatment group was 89.28% （P = 0.002）. Conclusions The effect of Tanreqing in children with acute jaundice hepatitis A was significantly better than that of conventional treatment.